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PubMed is a searchable database of medical literature and lists journal articles that discuss Mycobacterium Avium Complex infections. Click on the link to view a sample search on this topic. The AIDS Education and Training Center (AETC) offers information on Mycobacterium Avium Complex infections. Click on the link to view this information page. Shorthand is a system of writing that uses symbols to represent letters, words, or phrases. Writing with shorthand symbols allows you to write at a quicker speed than traditional handwriting. You will soon learn that shorthand is also used by many professionals, in places such as law courts. There is more than one type of shorthand writing. To use a keyboard shortcut, press and hold one or more modifier keys and then press the last key of the shortcut. For example, to use Command-C (copy), press and hold the Command key, then the C key, then release both keys. Mac menus and keyboards often use symbols for certain keys, including modifier keys: Command (or Cmd) ⌘.
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There are 3 types of MAC infections.
- Pulmonary MAC infections - Affect the lungs and are the most common type. These mainly affect elderly women and people who already have lung disease.[2][3]
- Disseminated MAC infections - Have spread throughout the body. This type is usually seen in people with advanced AIDS.[1]
- MAC-associated lymphadenitis - Causes swelling of the lymph nodes (especially in the neck) and is the most common in young children who have normal immune systems.[3][4]
The symptoms of pulmonary MAC infection start slowly, get worse over time and may last for weeks to months. People with pulmonary MAC infections may experience cough, weight loss, fever, fatigue, and night sweats.[2]
Symptoms of disseminated MAC infection include: [1][4]
- Fever
- Sweating
- Weight loss
- Fatigue
- Diarrhea
- Shortness of breath
- Abdominal pain
- Anemia
There have been a few reports of families with more than one family member with a MAC infection. In these families, it is thought that there is a variation in a gene or genes involved with the body's immune response. A genetic variant in an immune system gene may make some people more likely to get sick from an infection than others. There are many genes involved in the human immune response, and there is no single gene known to be responsible for MAC infections.[3][4]
Diagnosis of disseminated MAC infection is suspected based on symptoms and is confirmed in cultures of blood and often lymph node cells. Cultures of cells from urine, stool, liver or bone marrow may also be helpful. CT scans may be used to try to determine the different sites of infection in the body. If pulmonary or disseminated MAC infection is suspected, an HIV test may be done, as well as other tests, to rule out other associated medical conditions.[1][2][3]
A diagnosis of MAC lymphadenitis is confirmed by finding the bacteria in the culture of lymph node cells. These cells are collected by a biopsy of a swollen lymph node.[2][3]
- Pulmonary MAC infection, which affects the lungs
- Disseminated MAC infection, which affects many different parts of the body
- MAC lymphadenitis, which causes swollen lymph nodes
Treatment options for MAC infections vary by type of infection and by the presence of other medical conditions such as AIDS, cystic fibrosis, COPD, or cancer.[3]
Pulmonary MAC infections and disseminated MAC infections are usually treated with a combination of antibiotic medications. There are many types of antibiotics approved for treating MAC infections A combination of medicines is used because some of the disease-causing bacteria can be resistant to certain types of antibiotics. Using more than one antibiotic reduces the chance for the MAC bacteria to come back after treatment is over.[1][3]For people who have both HIV/AIDS and a MAC infection, treatment usually involves a combination of different antibiotics for the MAC infection and antiretroviral therapy to treat the HIV infection.[1][4]
In special circumstances, there is some evidence to suggest that surgery to remove a single spot of infection in one lung can be helpful in people who have had a poor response to drug therapy. Surgery is usually only done when the infection is found in only one lung and the surgery won't cause any long-term harm.[3][4]
Treatment of MAC lymphadenitis usually involves surgical removal of affected lymph nodes. Antibiotics may also be prescribed depending on the severity of infection and the response to surgery.[3][4]
FDA-Approved Treatments
The medication(s) listed below have been approved by the Food and Drug Administration (FDA) as orphan products for treatment of this condition. Learn more orphan products.- Liposomal amikacin(Brand name: Arikayce) - Manufactured by Insmed Incorporated
FDA-approved indication: September 2018, liposomal amikacin (Arikayce) was approved for the treatment of Mycobacterium avium complex (MAC) lung disease as part of a combination antibacterial drug regimen in patients who do not achieve negative sputum cultures after a minimum of 6 consecutive months of a multidrug background regimen therapy.
National Library of Medicine Drug Information Portal
Medline Plus Health Information
People who are HIV-positive with MAC infections may have a shortened lifespan depending on their immune systems and their response to HIV medications. For people who have had successful treatment, there is still a chance that the infection will come back, so people who have been sick from a MAC infection need to be monitored over time.[2][3]
In HIV-negative people with lung disease from a MAC infection, the treatment success rates range from 20-90% in different studies.[2] People with certain types of lung disease, people who are underweight, and people with anemia are more likely to have a poor outcome than other HIV-negative people affected by a MAC infection.
MAC lymphadenitis in children generally does not impact their health. In some cases, the condition may go away even without treatment.[3]
Research helps us better understand diseases and can lead to advances in diagnosis and treatment. This section provides resources to help you learn about medical research and ways to get involved.
Clinical Research Resources
- ClinicalTrials.gov lists trials that are related to Mycobacterium Avium Complex infections. Click on the link to go to ClinicalTrials.gov to read descriptions of these studies.
Please note: Studies listed on the ClinicalTrials.gov website are listed for informational purposes only; being listed does not reflect an endorsement by GARD or the NIH. We strongly recommend that you talk with a trusted healthcare provider before choosing to participate in any clinical study.
Support and advocacy groups can help you connect with other patients and families, and they can provide valuable services. Many develop patient-centered information and are the driving force behind research for better treatments and possible cures. They can direct you to research, resources, and services. Many organizations also have experts who serve as medical advisors or provide lists of doctors/clinics. Visit the group's website or contact them to learn about the services they offer. Inclusion on this list is not an endorsement by GARD.
Organizations Supporting this Disease
- NTM Info & Research (supports pulmonary NTM infections)
550 Madruga Avenue, Suite 230
Coral Gables, FL 33146
Telephone: 305-667-6461, ext 26 and 32
E-mail: ntmmail@ntminfo.org
Website: http://www.ntminfo.org/
These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional.
Where to Start
- The National Organization for Rare Disorders (NORD) has a report for patients and families about this condition. NORD is a patient advocacy organization for individuals with rare diseases and the organizations that serve them.
In-Depth Information
- Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
- The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch's tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Mycobacterium Avium Complex infections. Click on the link to view a sample search on this topic.
- The AIDS Education and Training Center (AETC) offers information on Mycobacterium Avium Complex infections. Click on the link to view this information page.
News
Rare Disease Day at NIH 2021
March 1, 2021
Questions sent to GARD may be posted here if the information could be helpful to others. We remove all identifying information when posting a question to protect your privacy. If you do not want your question posted, please let us know. Whats mac os x.
- Currier JS. Mycobacterium avium complex (MAC) infections in HIV-infected patients. UpToDate. 2017; https://www.uptodate.com/contents/mycobacterium-avium-complex-mac-infections-in-hiv-infected-patients.
- Griffith DE. Overview of nontuberculous mycobacterial infections in HIV-negative patients. UpToDate. 2017; https://www.uptodate.com/contents/overview-of-nontuberculous-mycobacterial-infections-in-hiv-negative-patients.
- Daley CL. Mycobacterium avium Complex Disease. Microbiol Spectr. April, 2017; 5(2):https://www.ncbi.nlm.nih.gov/pubmed/28429679.
- Koirala J. Mycobacterium Avium-Intracellulare. Medscape Reference. 2018; http://emedicine.medscape.com/article/222664-overview.
- Disseminated mycobacterium avium complex disease. US Department of Health and Human Services. 2017; https://aidsinfo.nih.gov/guidelines/html/4/adult-and-adolescent-opportunistic-infection/326/mac.
- Diel R, Lipman M, Hoefsloot W. High mortality in patients with Mycobacterium avium complex lung disease: a systematic review. BMC Infect Dis. 2018; 18(206):1-10. https://bmcinfectdis.biomedcentral.com/track/pdf/10.1186/s12879-018-3113-x.
To use a keyboard shortcut, press and hold one or more modifier keys and then press the last key of the shortcut. For example, to use Command-C (copy), press and hold the Command key, then the C key, then release both keys. Mac menus and keyboards often use symbols for certain keys, including modifier keys:
On keyboards made for Windows PCs, use the Alt key instead of Option, and the Windows logo key instead of Command.
Some keys on some Apple keyboards have special symbols and functions, such as for display brightness , keyboard brightness , Mission Control, and more. If these functions aren't available on your keyboard, you might be able to reproduce some of them by creating your own keyboard shortcuts. To use these keys as F1, F2, F3, or other standard function keys, combine them with the Fn key.
Cut, copy, paste, and other common shortcuts
Mac Medical Abbreviation
- Command-X: Cut the selected item and copy it to the Clipboard.
- Command-C: Copy the selected item to the Clipboard. This also works for files in the Finder.
- Command-V: Paste the contents of the Clipboard into the current document or app. This also works for files in the Finder.
- Command-Z: Undo the previous command. You can then press Shift-Command-Z to Redo, reversing the undo command. In some apps, you can undo and redo multiple commands.
- Command-A: Select All items.
- Command-F: Find items in a document or open a Find window.
- Command-G: Find Again: Find the next occurrence of the item previously found. To find the previous occurrence, press Shift-Command-G.
- Command-H: Hide the windows of the front app. To view the front app but hide all other apps, press Option-Command-H.
- Command-M: Minimize the front window to the Dock. To minimize all windows of the front app, press Option-Command-M.
- Command-O: Open the selected item, or open a dialog to select a file to open.
- Command-P: Print the current document.
- Command-S: Save the current document.
- Command-T: Open a new tab.
- Command-W: Close the front window. To close all windows of the app, press Option-Command-W.
- Option-Command-Esc: Force quit an app.
- Command–Space bar: Show or hide the Spotlight search field. To perform a Spotlight search from a Finder window, press Command–Option–Space bar. (If you use multiple input sources to type in different languages, these shortcuts change input sources instead of showing Spotlight. Learn how to change a conflicting keyboard shortcut.)
- Control–Command–Space bar: Show the Character Viewer, from which you can choose emoji and other symbols.
- Control-Command-F: Use the app in full screen, if supported by the app.
- Space bar: Use Quick Look to preview the selected item.
- Command-Tab: Switch to the next most recently used app among your open apps.
- Shift-Command-5: In macOS Mojave or later, take a screenshot or make a screen recording. Or use Shift-Command-3 or Shift-Command-4 for screenshots. Learn more about screenshots.
- Shift-Command-N: Create a new folder in the Finder.
- Command-Comma (,): Open preferences for the front app.
Sleep, log out, and shut down shortcuts
You might need to press and hold some of these shortcuts for slightly longer than other shortcuts. This helps you to avoid using them unintentionally.
- Power button: Press to turn on your Mac or wake it from sleep. Press and hold for 1.5 seconds to put your Mac to sleep.* Continue holding to force your Mac to turn off.
- Option–Command–Power button* or Option–Command–Media Eject : Put your Mac to sleep.
- Control–Shift–Power button* or Control–Shift–Media Eject : Put your displays to sleep.
- Control–Power button* or Control–Media Eject : Display a dialog asking whether you want to restart, sleep, or shut down.
- Control–Command–Power button:* Force your Mac to restart, without prompting to save any open and unsaved documents.
- Control–Command–Media Eject : Quit all apps, then restart your Mac. If any open documents have unsaved changes, you will be asked whether you want to save them.
- Control–Option–Command–Power button* or Control–Option–Command–Media Eject : Quit all apps, then shut down your Mac. If any open documents have unsaved changes, you will be asked whether you want to save them.
- Control-Command-Q: Immediately lock your screen.
- Shift-Command-Q: Log out of your macOS user account. You will be asked to confirm. To log out immediately without confirming, press Option-Shift-Command-Q.
There are 3 types of MAC infections.
- Pulmonary MAC infections - Affect the lungs and are the most common type. These mainly affect elderly women and people who already have lung disease.[2][3]
- Disseminated MAC infections - Have spread throughout the body. This type is usually seen in people with advanced AIDS.[1]
- MAC-associated lymphadenitis - Causes swelling of the lymph nodes (especially in the neck) and is the most common in young children who have normal immune systems.[3][4]
The symptoms of pulmonary MAC infection start slowly, get worse over time and may last for weeks to months. People with pulmonary MAC infections may experience cough, weight loss, fever, fatigue, and night sweats.[2]
Symptoms of disseminated MAC infection include: [1][4]
- Fever
- Sweating
- Weight loss
- Fatigue
- Diarrhea
- Shortness of breath
- Abdominal pain
- Anemia
There have been a few reports of families with more than one family member with a MAC infection. In these families, it is thought that there is a variation in a gene or genes involved with the body's immune response. A genetic variant in an immune system gene may make some people more likely to get sick from an infection than others. There are many genes involved in the human immune response, and there is no single gene known to be responsible for MAC infections.[3][4]
Diagnosis of disseminated MAC infection is suspected based on symptoms and is confirmed in cultures of blood and often lymph node cells. Cultures of cells from urine, stool, liver or bone marrow may also be helpful. CT scans may be used to try to determine the different sites of infection in the body. If pulmonary or disseminated MAC infection is suspected, an HIV test may be done, as well as other tests, to rule out other associated medical conditions.[1][2][3]
A diagnosis of MAC lymphadenitis is confirmed by finding the bacteria in the culture of lymph node cells. These cells are collected by a biopsy of a swollen lymph node.[2][3]
- Pulmonary MAC infection, which affects the lungs
- Disseminated MAC infection, which affects many different parts of the body
- MAC lymphadenitis, which causes swollen lymph nodes
Treatment options for MAC infections vary by type of infection and by the presence of other medical conditions such as AIDS, cystic fibrosis, COPD, or cancer.[3]
Pulmonary MAC infections and disseminated MAC infections are usually treated with a combination of antibiotic medications. There are many types of antibiotics approved for treating MAC infections A combination of medicines is used because some of the disease-causing bacteria can be resistant to certain types of antibiotics. Using more than one antibiotic reduces the chance for the MAC bacteria to come back after treatment is over.[1][3]For people who have both HIV/AIDS and a MAC infection, treatment usually involves a combination of different antibiotics for the MAC infection and antiretroviral therapy to treat the HIV infection.[1][4]
In special circumstances, there is some evidence to suggest that surgery to remove a single spot of infection in one lung can be helpful in people who have had a poor response to drug therapy. Surgery is usually only done when the infection is found in only one lung and the surgery won't cause any long-term harm.[3][4]
Treatment of MAC lymphadenitis usually involves surgical removal of affected lymph nodes. Antibiotics may also be prescribed depending on the severity of infection and the response to surgery.[3][4]
FDA-Approved Treatments
The medication(s) listed below have been approved by the Food and Drug Administration (FDA) as orphan products for treatment of this condition. Learn more orphan products.- Liposomal amikacin(Brand name: Arikayce) - Manufactured by Insmed Incorporated
FDA-approved indication: September 2018, liposomal amikacin (Arikayce) was approved for the treatment of Mycobacterium avium complex (MAC) lung disease as part of a combination antibacterial drug regimen in patients who do not achieve negative sputum cultures after a minimum of 6 consecutive months of a multidrug background regimen therapy.
National Library of Medicine Drug Information Portal
Medline Plus Health Information
People who are HIV-positive with MAC infections may have a shortened lifespan depending on their immune systems and their response to HIV medications. For people who have had successful treatment, there is still a chance that the infection will come back, so people who have been sick from a MAC infection need to be monitored over time.[2][3]
In HIV-negative people with lung disease from a MAC infection, the treatment success rates range from 20-90% in different studies.[2] People with certain types of lung disease, people who are underweight, and people with anemia are more likely to have a poor outcome than other HIV-negative people affected by a MAC infection.
MAC lymphadenitis in children generally does not impact their health. In some cases, the condition may go away even without treatment.[3]
Research helps us better understand diseases and can lead to advances in diagnosis and treatment. This section provides resources to help you learn about medical research and ways to get involved.
Clinical Research Resources
- ClinicalTrials.gov lists trials that are related to Mycobacterium Avium Complex infections. Click on the link to go to ClinicalTrials.gov to read descriptions of these studies.
Please note: Studies listed on the ClinicalTrials.gov website are listed for informational purposes only; being listed does not reflect an endorsement by GARD or the NIH. We strongly recommend that you talk with a trusted healthcare provider before choosing to participate in any clinical study.
Support and advocacy groups can help you connect with other patients and families, and they can provide valuable services. Many develop patient-centered information and are the driving force behind research for better treatments and possible cures. They can direct you to research, resources, and services. Many organizations also have experts who serve as medical advisors or provide lists of doctors/clinics. Visit the group's website or contact them to learn about the services they offer. Inclusion on this list is not an endorsement by GARD.
Organizations Supporting this Disease
- NTM Info & Research (supports pulmonary NTM infections)
550 Madruga Avenue, Suite 230
Coral Gables, FL 33146
Telephone: 305-667-6461, ext 26 and 32
E-mail: ntmmail@ntminfo.org
Website: http://www.ntminfo.org/
These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional.
Where to Start
- The National Organization for Rare Disorders (NORD) has a report for patients and families about this condition. NORD is a patient advocacy organization for individuals with rare diseases and the organizations that serve them.
In-Depth Information
- Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
- The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch's tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Mycobacterium Avium Complex infections. Click on the link to view a sample search on this topic.
- The AIDS Education and Training Center (AETC) offers information on Mycobacterium Avium Complex infections. Click on the link to view this information page.
News
Rare Disease Day at NIH 2021
March 1, 2021
Questions sent to GARD may be posted here if the information could be helpful to others. We remove all identifying information when posting a question to protect your privacy. If you do not want your question posted, please let us know. Whats mac os x.
- Currier JS. Mycobacterium avium complex (MAC) infections in HIV-infected patients. UpToDate. 2017; https://www.uptodate.com/contents/mycobacterium-avium-complex-mac-infections-in-hiv-infected-patients.
- Griffith DE. Overview of nontuberculous mycobacterial infections in HIV-negative patients. UpToDate. 2017; https://www.uptodate.com/contents/overview-of-nontuberculous-mycobacterial-infections-in-hiv-negative-patients.
- Daley CL. Mycobacterium avium Complex Disease. Microbiol Spectr. April, 2017; 5(2):https://www.ncbi.nlm.nih.gov/pubmed/28429679.
- Koirala J. Mycobacterium Avium-Intracellulare. Medscape Reference. 2018; http://emedicine.medscape.com/article/222664-overview.
- Disseminated mycobacterium avium complex disease. US Department of Health and Human Services. 2017; https://aidsinfo.nih.gov/guidelines/html/4/adult-and-adolescent-opportunistic-infection/326/mac.
- Diel R, Lipman M, Hoefsloot W. High mortality in patients with Mycobacterium avium complex lung disease: a systematic review. BMC Infect Dis. 2018; 18(206):1-10. https://bmcinfectdis.biomedcentral.com/track/pdf/10.1186/s12879-018-3113-x.
To use a keyboard shortcut, press and hold one or more modifier keys and then press the last key of the shortcut. For example, to use Command-C (copy), press and hold the Command key, then the C key, then release both keys. Mac menus and keyboards often use symbols for certain keys, including modifier keys:
On keyboards made for Windows PCs, use the Alt key instead of Option, and the Windows logo key instead of Command.
Some keys on some Apple keyboards have special symbols and functions, such as for display brightness , keyboard brightness , Mission Control, and more. If these functions aren't available on your keyboard, you might be able to reproduce some of them by creating your own keyboard shortcuts. To use these keys as F1, F2, F3, or other standard function keys, combine them with the Fn key.
Cut, copy, paste, and other common shortcuts
Mac Medical Abbreviation
- Command-X: Cut the selected item and copy it to the Clipboard.
- Command-C: Copy the selected item to the Clipboard. This also works for files in the Finder.
- Command-V: Paste the contents of the Clipboard into the current document or app. This also works for files in the Finder.
- Command-Z: Undo the previous command. You can then press Shift-Command-Z to Redo, reversing the undo command. In some apps, you can undo and redo multiple commands.
- Command-A: Select All items.
- Command-F: Find items in a document or open a Find window.
- Command-G: Find Again: Find the next occurrence of the item previously found. To find the previous occurrence, press Shift-Command-G.
- Command-H: Hide the windows of the front app. To view the front app but hide all other apps, press Option-Command-H.
- Command-M: Minimize the front window to the Dock. To minimize all windows of the front app, press Option-Command-M.
- Command-O: Open the selected item, or open a dialog to select a file to open.
- Command-P: Print the current document.
- Command-S: Save the current document.
- Command-T: Open a new tab.
- Command-W: Close the front window. To close all windows of the app, press Option-Command-W.
- Option-Command-Esc: Force quit an app.
- Command–Space bar: Show or hide the Spotlight search field. To perform a Spotlight search from a Finder window, press Command–Option–Space bar. (If you use multiple input sources to type in different languages, these shortcuts change input sources instead of showing Spotlight. Learn how to change a conflicting keyboard shortcut.)
- Control–Command–Space bar: Show the Character Viewer, from which you can choose emoji and other symbols.
- Control-Command-F: Use the app in full screen, if supported by the app.
- Space bar: Use Quick Look to preview the selected item.
- Command-Tab: Switch to the next most recently used app among your open apps.
- Shift-Command-5: In macOS Mojave or later, take a screenshot or make a screen recording. Or use Shift-Command-3 or Shift-Command-4 for screenshots. Learn more about screenshots.
- Shift-Command-N: Create a new folder in the Finder.
- Command-Comma (,): Open preferences for the front app.
Sleep, log out, and shut down shortcuts
You might need to press and hold some of these shortcuts for slightly longer than other shortcuts. This helps you to avoid using them unintentionally.
- Power button: Press to turn on your Mac or wake it from sleep. Press and hold for 1.5 seconds to put your Mac to sleep.* Continue holding to force your Mac to turn off.
- Option–Command–Power button* or Option–Command–Media Eject : Put your Mac to sleep.
- Control–Shift–Power button* or Control–Shift–Media Eject : Put your displays to sleep.
- Control–Power button* or Control–Media Eject : Display a dialog asking whether you want to restart, sleep, or shut down.
- Control–Command–Power button:* Force your Mac to restart, without prompting to save any open and unsaved documents.
- Control–Command–Media Eject : Quit all apps, then restart your Mac. If any open documents have unsaved changes, you will be asked whether you want to save them.
- Control–Option–Command–Power button* or Control–Option–Command–Media Eject : Quit all apps, then shut down your Mac. If any open documents have unsaved changes, you will be asked whether you want to save them.
- Control-Command-Q: Immediately lock your screen.
- Shift-Command-Q: Log out of your macOS user account. You will be asked to confirm. To log out immediately without confirming, press Option-Shift-Command-Q.
* Does not apply to the Touch ID sensor. Mac studio fix powder price.
Finder and system shortcuts
- Command-D: Duplicate the selected files.
- Command-E: Eject the selected disk or volume.
- Command-F: Start a Spotlight search in the Finder window.
- Command-I: Show the Get Info window for a selected file.
- Command-R: (1) When an alias is selected in the Finder: show the original file for the selected alias. (2) In some apps, such as Calendar or Safari, refresh or reload the page. (3) In Software Update preferences, check for software updates again.
- Shift-Command-C: Open the Computer window.
- Shift-Command-D: Open the desktop folder.
- Shift-Command-F: Open the Recents window, showing all of the files you viewed or changed recently.
- Shift-Command-G: Open a Go to Folder window.
- Shift-Command-H: Open the Home folder of the current macOS user account.
- Shift-Command-I: Open iCloud Drive.
- Shift-Command-K: Open the Network window.
- Option-Command-L: Open the Downloads folder.
- Shift-Command-N: Create a new folder.
- Shift-Command-O: Open the Documents folder.
- Shift-Command-P: Show or hide the Preview pane in Finder windows.
- Shift-Command-R: Open the AirDrop window.
- Shift-Command-T: Show or hide the tab bar in Finder windows.
- Control-Shift-Command-T: Add selected Finder item to the Dock (OS X Mavericks or later)
- Shift-Command-U: Open the Utilities folder.
- Option-Command-D: Show or hide the Dock.
- Control-Command-T: Add the selected item to the sidebar (OS X Mavericks or later).
- Option-Command-P: Hide or show the path bar in Finder windows.
- Option-Command-S: Hide or show the Sidebar in Finder windows.
- Command–Slash (/): Hide or show the status bar in Finder windows.
- Command-J: Show View Options.
- Command-K: Open the Connect to Server window.
- Control-Command-A: Make an alias of the selected item.
- Command-N: Open a new Finder window.
- Option-Command-N: Create a new Smart Folder.
- Command-T: Show or hide the tab bar when a single tab is open in the current Finder window.
- Option-Command-T: Show or hide the toolbar when a single tab is open in the current Finder window.
- Option-Command-V: Move the files in the Clipboard from their original location to the current location.
- Command-Y: Use Quick Look to preview the selected files.
- Option-Command-Y: View a Quick Look slideshow of the selected files.
- Command-1: View the items in the Finder window as icons.
- Command-2: View the items in a Finder window as a list.
- Command-3: View the items in a Finder window in columns.
- Command-4: View the items in a Finder window in a gallery.
- Command–Left Bracket ([): Go to the previous folder.
- Command–Right Bracket (]): Go to the next folder.
- Command–Up Arrow: Open the folder that contains the current folder.
- Command–Control–Up Arrow: Open the folder that contains the current folder in a new window.
- Command–Down Arrow: Open the selected item.
- Right Arrow: Open the selected folder. This works only when in list view.
- Left Arrow: Close the selected folder. This works only when in list view.
- Command-Delete: Move the selected item to the Trash.
- Shift-Command-Delete: Empty the Trash.
- Option-Shift-Command-Delete: Empty the Trash without confirmation dialog.
- Command–Brightness Down: Turn video mirroring on or off when your Mac is connected to more than one display.
- Option–Brightness Up: Open Displays preferences. This works with either Brightness key.
- Control–Brightness Up or Control–Brightness Down: Change the brightness of your external display, if supported by your display.
- Option–Shift–Brightness Up or Option–Shift–Brightness Down: Adjust the display brightness in smaller steps. Add the Control key to this shortcut to make the adjustment on your external display, if supported by your display.
- Option–Mission Control: Open Mission Control preferences.
- Command–Mission Control: Show the desktop.
- Control–Down Arrow: Show all windows of the front app.
- Option–Volume Up: Open Sound preferences. This works with any of the volume keys.
- Option–Shift–Volume Up or Option–Shift–Volume Down: Adjust the sound volume in smaller steps.
- Option–Keyboard Brightness Up: Open Keyboard preferences. This works with either Keyboard Brightness key.
- Option–Shift–Keyboard Brightness Up or Option–Shift–Keyboard Brightness Down: Adjust the keyboard brightness in smaller steps.
- Option key while double-clicking: Open the item in a separate window, then close the original window.
- Command key while double-clicking: Open a folder in a separate tab or window.
- Command key while dragging to another volume: Move the dragged item to the other volume, instead of copying it.
- Option key while dragging: Copy the dragged item. The pointer changes while you drag the item.
- Option-Command while dragging: Make an alias of the dragged item. The pointer changes while you drag the item.
- Option-click a disclosure triangle: Open all folders within the selected folder. This works only when in list view.
- Command-click a window title: See the folders that contain the current folder.
- Learn how to use Command or Shift to select multiple items in the Finder.
- Click the Go menu in the Finder menu bar to see shortcuts for opening many commonly used folders, such as Applications, Documents, Downloads, Utilities, and iCloud Drive.
Document shortcuts
The behavior of these shortcuts may vary with the app you're using.
- Command-B: Boldface the selected text, or turn boldfacing on or off.
- Command-I: Italicize the selected text, or turn italics on or off.
- Command-K: Add a web link.
- Command-U: Underline the selected text, or turn underlining on or off.
- Command-T: Show or hide the Fonts window.
- Command-D: Select the Desktop folder from within an Open dialog or Save dialog.
- Control-Command-D: Show or hide the definition of the selected word.
- Shift-Command-Colon (:): Display the Spelling and Grammar window.
- Command-Semicolon (;): Find misspelled words in the document.
- Option-Delete: Delete the word to the left of the insertion point.
- Control-H: Delete the character to the left of the insertion point. Or use Delete.
- Control-D: Delete the character to the right of the insertion point. Or use Fn-Delete.
- Fn-Delete: Forward delete on keyboards that don't have a Forward Delete key. Or use Control-D.
- Control-K: Delete the text between the insertion point and the end of the line or paragraph.
- Fn–Up Arrow: Page Up: Scroll up one page.
- Fn–Down Arrow: Page Down: Scroll down one page.
- Fn–Left Arrow: Home: Scroll to the beginning of a document.
- Fn–Right Arrow: End: Scroll to the end of a document.
- Command–Up Arrow: Move the insertion point to the beginning of the document.
- Command–Down Arrow: Move the insertion point to the end of the document.
- Command–Left Arrow: Move the insertion point to the beginning of the current line.
- Command–Right Arrow: Move the insertion point to the end of the current line.
- Option–Left Arrow: Move the insertion point to the beginning of the previous word.
- Option–Right Arrow: Move the insertion point to the end of the next word.
- Shift–Command–Up Arrow: Select the text between the insertion point and the beginning of the document.
- Shift–Command–Down Arrow: Select the text between the insertion point and the end of the document.
- Shift–Command–Left Arrow: Select the text between the insertion point and the beginning of the current line.
- Shift–Command–Right Arrow: Select the text between the insertion point and the end of the current line.
- Shift–Up Arrow: Extend text selection to the nearest character at the same horizontal location on the line above.
- Shift–Down Arrow: Extend text selection to the nearest character at the same horizontal location on the line below.
- Shift–Left Arrow: Extend text selection one character to the left.
- Shift–Right Arrow: Extend text selection one character to the right.
- Option–Shift–Up Arrow: Extend text selection to the beginning of the current paragraph, then to the beginning of the following paragraph if pressed again.
- Option–Shift–Down Arrow: Extend text selection to the end of the current paragraph, then to the end of the following paragraph if pressed again.
- Option–Shift–Left Arrow: Extend text selection to the beginning of the current word, then to the beginning of the following word if pressed again.
- Option–Shift–Right Arrow: Extend text selection to the end of the current word, then to the end of the following word if pressed again.
- Control-A: Move to the beginning of the line or paragraph.
- Control-E: Move to the end of a line or paragraph.
- Control-F: Move one character forward.
- Control-B: Move one character backward.
- Control-L: Center the cursor or selection in the visible area.
- Control-P: Move up one line.
- Control-N: Move down one line.
- Control-O: Insert a new line after the insertion point.
- Control-T: Swap the character behind the insertion point with the character in front of the insertion point.
- Command–Left Curly Bracket ({): Left align.
- Command–Right Curly Bracket (}): Right align.
- Shift–Command–Vertical bar (|): Center align.
- Option-Command-F: Go to the search field.
- Option-Command-T: Show or hide a toolbar in the app.
- Option-Command-C: Copy Style: Copy the formatting settings of the selected item to the Clipboard.
- Option-Command-V: Paste Style: Apply the copied style to the selected item.
- Option-Shift-Command-V: Paste and Match Style: Apply the style of the surrounding content to the item pasted within that content.
- Option-Command-I: Show or hide the inspector window.
- Shift-Command-P: Page setup: Display a window for selecting document settings.
- Shift-Command-S: Display the Save As dialog, or duplicate the current document.
- Shift–Command–Minus sign (-): Decrease the size of the selected item.
- Shift–Command–Plus sign (+): Increase the size of the selected item. Command–Equal sign (=) performs the same function.
- Shift–Command–Question mark (?): Open the Help menu.
Other shortcuts
For more shortcuts, check the shortcut abbreviations shown in the menus of your apps. Every app can have its own shortcuts, and shortcuts that work in one app might not work in another.
- Apple Music shortcuts: Choose Help > Keyboard shortcuts from the menu bar in the Music app.
- Other shortcuts: Choose Apple menu > System Preferences, click Keyboard, then click Shortcuts.
Learn more
Abbreviation Dictionary List Of Abbreviations
- Create your own shortcuts and resolve conflicts between shortcuts
- Change the behavior of the function keys or modifier keys